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Pathogenetic treatment of central
chorioretinal
dystrophies with picamilon
[Article in Russian]
Basinskii SN, Krasnogorskaia VN,
Lenis IuA.
Vestn Oftalmol 2001 Mar-Apr;117(2):42-4
Abstract
Picamilon was used in the
treatment of 48 patients with central chorioretinal dystrophies. In
group 1 (34 eyes) the drug was delivered to the posterior pole of the eye
through an infusion collagen system, which was followed by He-Ne laser
exposure. In group 2 (46 eyes) the patients were given picamilon
tablets. The following examinations were carried out in all patients before
and immediately after treatment: evaluation of visual acuity, borders of
peripheral visual field, critical frequency of fusion of flashes,
visocontrastometry, electroretinography with consideration for pathological
changes in the retina, rheography, direct and indirect ophthalmoscopy.
Electric sensitivity and electric lability of the retina were evaluated and
the function of the off/on channels examined. Subjective and objective
parameters improved both in the first and second groups (in 98 and 65%,
respectively). Picamilon promoted extension of the peripheral borders
of visual field, improved contrast sensitivity, and increased the velocity
of the sensorimotor reaction, which indicated improvement of interactions
between neurons and of receptor function.
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